Shaoxiang Wang Selected Research

SNX 2112

8/2015	Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.
1/2015	Comparative effects of SNX-7081 and SNX-2112 on cell cycle, apoptosis and Hsp90 client proteins in human cancer cells.
1/2015	Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells.
3/2014	The Hsp90 inhibitor SNX-2112 induces apoptosis of human hepatocellular carcinoma cells: the role of ER stress.
9/2013	The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways.

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Shaoxiang Wang Research Topics

Disease

13	Neoplasms (Cancer) 01/2022 - 09/2013
6	Esophageal Squamous Cell Carcinoma 01/2022 - 01/2014
6	Infections 07/2019 - 08/2012
4	Neoplasm Metastasis (Metastasis) 01/2022 - 12/2015
4	Esophageal Neoplasms (Esophageal Cancer) 01/2022 - 01/2015
2	Colonic Neoplasms (Colon Cancer) 01/2021 - 01/2020
1	Glioma (Gliomas) 01/2022
1	Obesity 01/2021
1	Carcinogenesis 01/2021
1	Colorectal Neoplasms (Colorectal Cancer) 02/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020
1	Wounds and Injuries (Trauma) 07/2019
1	Lymphatic Metastasis 01/2019
1	Stomach Neoplasms (Stomach Cancer) 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Breast Neoplasms (Breast Cancer) 12/2015
1	Hepatocellular Carcinoma (Hepatoma) 03/2014
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 09/2013
1	Leukemia 09/2013
1	Virus Diseases (Viral Diseases) 08/2012

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2013
5	SNX 2112IBA 08/2015 - 09/2013
4	Pharmaceutical PreparationsIBA 01/2022 - 04/2014
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2020
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 08/2015 - 09/2013
3	Actin Depolymerizing Factors (Cofilins)IBA 01/2014 - 08/2012
2	MicroRNAs (MicroRNA)IBA 02/2020 - 06/2018
2	Fluorouracil (Carac)FDA LinkGeneric 01/2016 - 01/2015
2	Actins (F Actin)IBA 01/2014 - 08/2012
1	Exportin 1 ProteinIBA 01/2022
1	verdinexorIBA 01/2022
1	vasectrin IIIIBA 01/2022
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2021
1	Angiotensin-Converting Enzyme 2IBA 01/2021
1	Hormones (Hormone)IBA 01/2021
1	CyclinsIBA 01/2021
1	Proto-Oncogene Proteins c-etsIBA 01/2021
1	Cyclin B1IBA 01/2021
1	Cyclin A2IBA 01/2021
1	Serine Proteases (Serine Protease)IBA 01/2021
1	Circular RNAIBA 02/2020
1	Messenger RNA (mRNA)IBA 02/2020
1	Indicators and Reagents (Reagents)IBA 01/2020
1	CXC ChemokinesIBA 01/2020
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2020
1	methyllycaconitineIBA 01/2020
1	Citric Acid (Citrate)FDA LinkGeneric 01/2020
1	Nicotine FDA Link 01/2020
1	Cholinergic Agents (Cholinergics)IBA 01/2020
1	Matrix Metalloproteinases (MMPs)IBA 01/2020
1	ChitosanIBA 07/2019
1	Minocycline (Cyclops)FDA LinkGeneric 07/2019
1	PolyelectrolytesIBA 07/2019
1	Polysaccharides (Glycans)IBA 07/2019
1	CollagenIBA 01/2019
1	ClusterinIBA 01/2019
1	Verteporfin (Visudyne)FDA Link 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	Glycoproteins (Glycoprotein)IBA 01/2018
1	ginsenoside RoIBA 01/2016
1	CathepsinsIBA 01/2016
1	Raloxifene Hydrochloride (Evista)FDA Link 12/2015
1	Sulfates (Sulfates, Inorganic)IBA 12/2015
1	Multidrug Resistance-Associated ProteinsIBA 12/2015
1	monoamine-sulfating phenol sulfotransferaseIBA 12/2015
1	Hematoxylin (Haematoxylon)IBA 08/2015
1	Eosine Yellowish-(YS) (Eosin)IBA 08/2015
1	Cyclin D1IBA 08/2015
1	Cisplatin (Platino)FDA LinkGeneric 01/2015
1	SNX-7081IBA 01/2015
1	tanespimycin (17AAG)IBA 07/2014
1	geldanamycinIBA 07/2014
1	Viral RNAIBA 04/2014
1	Tamoxifen FDA LinkGeneric 04/2014
1	5-nitro-2-(3-phenylpropylamino)benzoic acidIBA 04/2014
1	Ion Channels (Ion Channel)IBA 04/2014
1	ChloridesIBA 04/2014
1	Antiviral Agents (Antivirals)IBA 04/2014
1	Adenosine Triphosphate (ATP)IBA 09/2013
1	Molecular Chaperones (Chaperone, Molecular)IBA 09/2013
1	Destrin (Actin Depolymerizing Factor)IBA 08/2012
1	Cofilin 1IBA 08/2012

Therapy/Procedure

5	Therapeutics 01/2021 - 03/2014
2	Chronotherapy 01/2022 - 01/2021
2	Drug Therapy (Chemotherapy) 01/2015 - 09/2013
1	Radical Mastectomy 12/2015
1	Intraperitoneal Injections 08/2015